Impending Hemorrhagic Shock

By blocking sympathogenic vasoconstrictor mechanisms with dibenamine, a dog's tolerance to severe hemorrhagic hypotension states is definitely improved. New evidence is presented that partial release from vasoconstriction achieved by, giving small doses of dibenamine during the impending shock state seems to provide animals with even greater tolerance to this standardized form of stress. Although the use of dibenamine clinically for this purpose seems contraindicated, the dangers of at(lministering vasoconstrictor drugs to patients in impending shock are emphasized.